Michail Sitkovsky

Michail Sitkovsky

Company: Northeastern University

Job title: Professor & Director

Seminars:

The Discovery of Biochemical & Immunological Mechanisms of the Hypoxia- A2-Adenosinergic Immunosuppression as the Foundation of the Conceptually Novel Immunotherapies of Cancer Using Several Classes of Anti-Hypoxia-A2- Adenosingergic Drugs 9:10 am

• Highlighting that extracellular adenosine-A2AR/A2BR adenosine receptors-cyclic AMP-PKA axis: provides the “OFF” signal to TCR activated T-Cells and inhibit NK cells and other immune cells, triggers the immunosuppressive transcription of all other known immunosuppressive molecules like PD1 via cAMP Response Element (CRE) and CREB transcription factor • Discussing that i) inhibition of adenosine-generating enzymes like…Read more

day: Day One

© Copyright 2022 Hanson Wade | Design and site by Event Engine | Hanson Wade Limited is registered in England & Wales, number 06752216.
Registered Office: Suite A, 6 Honduras Street, London EC1Y 0TH.