Adenosine-Mediated Immune Cell Inhibition
Time: 9:00 am - 12:00 pm
day: Pre-Conference Day
Details:
Adenosine’s role in cancer progression is well-explored, but with this amount of data, it can be hard to determine the usable insights. Join this workshop to take a granular look at internal and external adenosine pathways. You will learn Tumor immunosuppression mechanisms and their effects on CD8+ T cells.
- Focus on the role of enzyme related changes vs. adenosine receptor changes
- Explore the role of adenosine internally and externally in driving immune suppression and tumor growth and metastasis
- Highlight the complexity and redundancy of purine-converting pathways in the tumor microenvironment
- Consider the functions of adenosine kinase as potential therapeutic target
